{"id":173037,"date":"2024-11-26T09:15:08","date_gmt":"2024-11-26T12:15:08","guid":{"rendered":"https:\/\/controllab.com\/colaboracao-entre-opas-iec-e-controllab-promove-mais-confiabilidade-para-deteccao-do-virus-oropouche\/"},"modified":"2024-11-26T15:42:27","modified_gmt":"2024-11-26T18:42:27","slug":"collaboration-between-paho-iec-and-controllab-enhances-reliability-in-the-detection-of-the-oropouche-virus","status":"publish","type":"post","link":"https:\/\/controllab.com\/en\/collaboration-between-paho-iec-and-controllab-enhances-reliability-in-the-detection-of-the-oropouche-virus\/","title":{"rendered":"Collaboration between PAHO, IEC, and Controllab enhances reliability in the detection of the Oropouche virus"},"content":{"rendered":"\t\t
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An initiative by the Pan American Health Organization (PAHO) and the Evandro Chagas Institute aimed to enhance professionals’ routines and strengthen virus surveillance efforts across the Americas.<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The Pan American Health Organization (PAHO)<\/a> and the Evandro Chagas Institute (IEC)<\/a>, a science and technology institution under the Secretariat for Health Surveillance and Environment (SVSA) of the Ministry of Health<\/a> (Brazil), held the workshop \u201cSerological and Molecular Detection of Oropouche Virus (OROV) Infection<\/a>\u201d in September and October 2024.<\/p>\n

The initiative arose from the need to strengthen virus surveillance efforts across the Americas and was conducted at the Arbovirology and Hemorrhagic Fevers Section (SEARB), which serves as a National Reference Laboratory and a Collaborating Center for PAHO and the World Health Organization (WHO) for emerging and re-emerging arboviruses and other viral zoonoses.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Professional development and benefits for public health<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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According to PAHO and IEC, laboratory diagnosis of OROV infection is essential for case confirmation and the qualification of surveillance data. The expectation is that, following the workshop, professionals will apply the knowledge gained regarding OROV diagnosis in both molecular and serological routine diagnostics, in order to strengthen the surveillance system. This way, it will be possible to improve the timely detection of outbreaks, monitor cases, and guide evidence-based decision-making.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Controllab and its contribution to the workshop<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Attuned to the needs of the diagnostic sector and recognized for pioneering initiatives that ensure reliability in analytical routines, Controllab<\/a>, the first company to provide the Proficiency Testing for Molecular Biology of the Oropouche Virus<\/a>, sent control material samples for the training of professionals.<\/p>\n

PAHO and IEC emphasize the importance of Controllab’s collaboration, an international reference in laboratory quality control solutions:<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u2013 Currently, the availability of serological tests for detecting OROV infection is limited. Most countries in the region that have OROV diagnostics rely on the detection of viral genetic material through RT-qPCR. In this context, it is essential to ensure the quality and reliability of the results obtained in various public health laboratories across the region. The variety of samples and the complexity of the panels proposed by these tests allow for the assessment of laboratories’ ability to detect the virus under different conditions, simulating real-world diagnostic scenarios.<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Como o Ensaio de Profici\u00eancia contribui para a confiabilidade diagn\u00f3stica?<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Laboratory routines require continuous monitoring and periodic evaluation, as they play a critical role in the processes of detection, assessment, response, reporting, and monitoring of public health events.<\/p>\n

Proficiency Testing (PT)<\/a>, also known as External Quality Control<\/strong>, is an effective tool for determining the laboratory’s analytical performance, assisting in the standardization of new diagnostic tests for the disease. In addition, it is a necessary requirement for laboratory accreditation processes (ISO 15189, ISO 17025, PALC-SBPC\/ML, DICQ-SBAC, etc.) and regulatory bodies.<\/p>\n

PAHO and IEC emphasized that conducting Proficiency Testing for Molecular Biology in the diagnosis of Oropouche virus (OROV), such as those offered by Controllab, is essential to ensure the quality and reliability<\/strong> of laboratory results:<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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– Ao identificar poss\u00edveis falhas e desvios nos resultados, os Ensaios de Profici\u00eancia contribuem para a melhoria cont\u00ednua das pr\u00e1ticas laboratoriais e para a padroniza\u00e7\u00e3o dos m\u00e9todos de diagn\u00f3stico. Isso \u00e9 crucial para garantir a comparabilidade dos resultados entre diferentes laborat\u00f3rios e fortalecer a vigil\u00e2ncia epidemiol\u00f3gica. Al\u00e9m disso, a qualidade dos dados gerados por meio de testes de profici\u00eancia robustos influencia diretamente a tomada de decis\u00f5es em sa\u00fade p\u00fablica, permitindo a implementa\u00e7\u00e3o de medidas de controle mais eficazes e a aloca\u00e7\u00e3o adequada de recursos.<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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According to PAHO and IEC, the implementation of Proficiency Testing<\/strong> is essential to ensure the quality, reliability, sensitivity, and specificity of tests; harmonization and standardization between laboratories; technical training; and continuous improvement.<\/p>\n

In summary, it is crucial to ensure that laboratories have the technical capacity to perform reliable diagnostics<\/strong> and to support decision-making in public health, especially in a context of rapid virus spread and limited resources for diagnosis.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Epidemiological situation<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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On October 15, 2024, PAHO released the epidemiological situation of Oropouche in the Americas: between epidemiological weeks (EW) 1 and 40 of 2024, 10,275 cases of Oropouche were confirmed, including two deaths. The cases were reported in nine countries: Bolivia, Brazil, Canada, Colombia, Cuba, Ecuador, United States of America, Guyana, and Peru.<\/p>\n

In this context, Brazil reported 13 fetal deaths, three spontaneous abortions, and four cases of congenital anomalies. In September, Cuba confirmed one case of congenital anomaly.<\/p>\n

Clicking on this link<\/a>, you can check the updated epidemiological situation of the Oropouche virus.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Strengthening epidemiological surveillance in the Americas<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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PAHO periodically provides updated epidemiological information and data. To guide the health systems of countries, the organization has made available documents such as:<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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