{"id":199161,"date":"2025-10-13T08:00:51","date_gmt":"2025-10-13T11:00:51","guid":{"rendered":"https:\/\/controllab.com\/contaminacoes-em-medicamentos-como-monitorar-a-seguranca-dos-seus-processos\/"},"modified":"2025-10-13T08:16:33","modified_gmt":"2025-10-13T11:16:33","slug":"contamination-in-medicines-how-to-monitor-the-safety-of-your-processes","status":"publish","type":"post","link":"https:\/\/controllab.com\/en\/contamination-in-medicines-how-to-monitor-the-safety-of-your-processes\/","title":{"rendered":"Contamination in medicines: how to monitor the safety of your processes?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"199161\" class=\"elementor elementor-199161 elementor-197194\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"has_ae_slider elementor-element elementor-element-622a39f e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"622a39f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f9b8df elementor-widget elementor-widget-text-editor\" data-id=\"8f9b8df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Controllab\u2019s Proficiency Testing programs are strategic allies for evaluating laboratory routines and reinforcing the reliability of results.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-2a0f725 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"2a0f725\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0c85976 elementor-widget elementor-widget-text-editor\" data-id=\"0c85976\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"220\" data-end=\"1023\">Pharmaceutical products require strict quality controls to ensure the safety and health of the population. A <a href=\"https:\/\/www.theguardian.com\/world\/2025\/aug\/14\/argentina-contaminated-fentanyl?CMP=share_btn_url\" target=\"_blank\" rel=\"noopener\">recent incident in Argentina<\/a> highlights the seriousness of this responsibility: contaminated fentanyl batches caused severe infections by <em data-start=\"467\" data-end=\"490\">Klebsiella pneumoniae<\/em> and <em data-start=\"495\" data-end=\"516\">Ralstonia pickettii<\/em>, some strains resistant to multiple antibiotics, resulting in fatal clinical outcomes for dozens of patients.<\/p><p data-start=\"220\" data-end=\"1023\">Cases like this underscore the importance of practices that ensure the reliability of analytical results and, consequently, the quality of products made available on the market. In this context, <a href=\"https:\/\/controllab.com\/en\" target=\"_blank\" rel=\"noopener\">Controllab<\/a>, a leader in laboratory quality control in Latin America, offers <a href=\"https:\/\/controllab.com\/en\/solutions\/proficiency-testing\/\" target=\"_blank\" rel=\"noopener\">Proficiency Testing (PT)<\/a> programs designed for laboratories working with Sterile and Non-Sterile Pharmaceutical Products.<\/p><p data-start=\"1025\" data-end=\"1400\">These programs evaluate analytical performance using control samples recognized by the <em>Coordena\u00e7\u00e3o-Geral de Acredita\u00e7\u00e3o do Inmetro<\/em> (<a href=\"https:\/\/www.gov.br\/inmetro\/pt-br\/assuntos\/acreditacao-reconhecimento-bpl\/organismos-acreditados\/provedores-de-ensaios-de-proficiencia\/escopos\/pep0003.pdf\" target=\"_blank\" rel=\"noopener\">PEP 0003<\/a>), Brazil\u2019s accreditation authority. Comparing results with other participants and analyzing the outcomes allows laboratories to detect and correct analytical deviations, improve process efficiency and safety, and demonstrate regulatory and normative compliance.<\/p><p data-start=\"1402\" data-end=\"1443\" data-is-last-node=\"\" data-is-only-node=\"\">The programs include the following tests:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-c59de84 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"c59de84\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2a7dafe elementor-widget elementor-widget-html\" data-id=\"2a7dafe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!DOCTYPE html>\r\n<html lang=\"pt\">\r\n<head>\r\n\t<meta charset=\"UTF-8\">\r\n\t<meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\r\n\t<title>Tabela<\/title>\r\n<\/head>\r\n<body>\r\n\t<table\r\n\tstyle=\"max-width: 100%; margin: 30px auto 0px auto; font-family: 'Geometria', Arial, sans-serif; font-size: 16px; font-weight: 400; color: #706e6d; line-height: 1.5; background-color: #ffffff; border-bottom-left-radius: 8px; border-bottom-right-radius: 8px; border-top-left-radius: 8px; border-top-right-radius: 8px; border: thin solid #dadce0;\"\r\n\tborder=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#e4e8e5\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Programs<\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#f2f2f2\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Tests<\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#f2f2f2\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Accreditation<\/p>\r\n\t\t\t<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: left;\"><a style=\"text-align: left; color: #007d4b; font-weight: bold; font-family: &#039;Geometria&#039;; text-decoration: none;\" href=\"https:\/\/controllab.com\/en\/program\/sterile-products\/\" target=\"_blank\" rel=\"noopener\">Sterile Pharmaceutical <br>Products I<\/a><\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: left\">\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left\"><strong>Sterility testing in pharmaceutical raw materials, injectable medicines, ophthalmic solutions, and healthcare products.<\/strong><\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: center;\"><a style=\"display: inline; vertical-align: middle; font-size: 12px; color: #f4b91a; font-weight: 500; font-family: &#039;Geometria&#039;; text-decoration: none; text-transform: uppercase;\" href=\"https:\/\/controllab.com\/programa\/produtos-estereis\/#pep-0003\" target=\"_blank\" rel=\"noopener\"><img style=\"height: 28px; vertical-align: middle; margin-right: 5px;\"\r\n\t\t\t\t\t\ttitle=\"Ensaio de Profici\u00eancia\"\r\n\t\t\t\t\t\tsrc=\"https:\/\/controllab.com\/wp-content\/uploads\/PEP-0003-ABNT-NBR-ISO-IEC-17043-Controllab.png\"\r\n\t\t\t\t\t\talt=\"Ensaio de Profici\u00eancia\" \/><\/a><\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: left;\"><a style=\"text-align: left; color: #007d4b; font-weight: bold; font-family: &#039;Geometria&#039;; text-decoration: none;\" href=\"https:\/\/controllab.com\/en\/program\/non-sterile-pharmaceutical-products\/\" target=\"_blank\" rel=\"noopener\">Non-Sterile Pharmaceutical <br>Products I<\/a><\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px text-align: left;\">\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left;\"><strong>Total aerobic mesophilic microorganism count<\/strong><\/p>\r\n\t\t\t  <p style=\"line-height: 18px; text-align: left\"><strong>Search for:<\/strong><\/p>\r\n\t\t\t  \r\n\t\t\t  <p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Fecal Coliforms<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Bile-tolerant Gram-negative bacteria in oral and topical medicines<\/p>\r\n\t\t  <\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: center;\"><a style=\"display: inline; vertical-align: middle; font-size: 12px; color: #f4b91a; font-weight: 500; font-family: &#039;Geometria&#039;; text-decoration: none; text-transform: uppercase;\" href=\"https:\/\/controllab.com\/programa\/produtos-farmaceuticos-nao-estereis\/#pep-0003\" target=\"_blank\" rel=\"noopener\"><img style=\"height: 28px; vertical-align: middle; margin-right: 5px;\"\r\n\t\t\t\t\t\ttitle=\"Ensaio de Profici\u00eancia\"\r\n\t\t\t\t\t\tsrc=\"https:\/\/controllab.com\/wp-content\/uploads\/PEP-0003-ABNT-NBR-ISO-IEC-17043-Controllab.png\"\r\n\t\t\t\t\t\talt=\"Ensaio de Profici\u00eancia\" \/><\/a><\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n<\/body>\r\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-a928460 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"a928460\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-96ea911 elementor-widget elementor-widget-text-editor\" data-id=\"96ea911\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Controllab also offers other programs that support laboratory routines and reinforce the reliability of results. These are:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-708b23a e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"708b23a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-43446f5 elementor-widget elementor-widget-html\" data-id=\"43446f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!DOCTYPE html>\r\n<html lang=\"pt\">\r\n<head>\r\n\t<meta charset=\"UTF-8\">\r\n\t<meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\r\n\t<title>Tabela<\/title>\r\n<\/head>\r\n<body>\r\n\t<table\r\n\tstyle=\"max-width: 100%; margin: 30px auto 0px auto; font-family: 'Geometria', Arial, sans-serif; font-size: 16px; font-weight: 400; color: #706e6d; line-height: 1.5; background-color: #ffffff; border-bottom-left-radius: 8px; border-bottom-right-radius: 8px; border-top-left-radius: 8px; border-top-right-radius: 8px; border: thin solid #dadce0;\"\r\n\tborder=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\r\n\t<tbody>\r\n\t\t<tr>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#f2f2f2\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Programs<\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#f2f2f2\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Tests<\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"background: #f2f2f2; padding: 10px;\" bgcolor=\"#f2f2f2\">\r\n\t\t\t\t<p style=\"text-align: center; font-weight: bold; line-height: 18px; margin-top: 15px\">Accreditation<\/p>\r\n\t\t\t<\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: left;\"><a style=\"text-align: center; color: #007d4b; font-weight: bold; font-family: &#039;Geometria&#039;; text-decoration: none;\" href=\"https:\/\/controllab.com\/en\/program\/sterile-products\/\" target=\"_blank\" rel=\"noopener\">Sterile Pharmaceutical<br> Products II<\/a><\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px;\">\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left\"><strong>Mold and yeast (fungi) count<\/strong><\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left\"><strong>Sterile II (Detection \/1 mL)<\/strong><\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left\"><strong>Search for:<\/strong><\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Clostridia<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Sulfite-reducing Clostridia<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- <em>Clostridium perfringens<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Staphylococcus aureus<\/p><\/em>\r\n\t\t\t\t\r\n\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: center;\"><a style=\"display: inline; vertical-align: middle; font-size: 12px; color: #f4b91a; font-weight: 500; font-family: &#039;Geometria&#039;; text-decoration: none; text-transform: uppercase;\" href=\"https:\/\/controllab.com\/programa\/produtos-estereis\/#pep-0003\" target=\"_blank\" rel=\"noopener\"><img style=\"height: 28px; vertical-align: middle; margin-right: 5px;\"\r\n\t\t\t\t\t\ttitle=\"Ensaio de Profici\u00eancia\"\r\n\t\t\t\t\t\tsrc=\"https:\/\/controllab.com\/wp-content\/uploads\/PEP-0003-ABNT-NBR-ISO-IEC-17043-Controllab.png\"\r\n\t\t\t\t\t\talt=\"Ensaio de Profici\u00eancia\" \/><\/a><\/td>\r\n\t\t<\/tr>\r\n\t\t<tr>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: left;\"><a style=\"text-align: center; color: #007d4b; font-weight: bold; font-family: &#039;Geometria&#039;; text-decoration: none;\" href=\"https:\/\/controllab.com\/en\/program\/non-sterile-pharmaceutical-products\/\" target=\"_blank\" rel=\"noopener\">Non-Sterile Pharmaceutical <br>Products II<\/a><\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px;\">\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left;\"><strong>Mold and yeast count<\/strong><\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left\"><strong>Search for:<\/strong><\/p>\r\n\t\t\t  <p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- <em>Candida albicans<\/em><\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Clostridia<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Sulfite-reducing Clostridia<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">-<em> Clostridium perfringens<\/p>\r\n\t\t\t\t<p style=\"line-height: 18px; text-align: left; padding-left: 10px\">- Staphylococcus aureus<\/em><\/p>\r\n\t\t\t<\/td>\r\n\t\t\t<td style=\"border: 1px solid #e0e0e0; padding: 10px; text-align: center;\"><a style=\"display: inline; vertical-align: middle; font-size: 12px; color: #f4b91a; font-weight: 500; font-family: &#039;Geometria&#039;; text-decoration: none; text-transform: uppercase;\" href=\"https:\/\/controllab.com\/programa\/produtos-farmaceuticos-nao-estereis\/#pep-0003\" target=\"_blank\" rel=\"noopener\"><img style=\"height: 28px; vertical-align: middle; margin-right: 5px;\"\r\n\t\t\t\t\t\ttitle=\"Ensaio de Profici\u00eancia\"\r\n\t\t\t\t\t\tsrc=\"https:\/\/controllab.com\/wp-content\/uploads\/PEP-0003-ABNT-NBR-ISO-IEC-17043-Controllab.png\"\r\n\t\t\t\t\t\talt=\"Ensaio de Profici\u00eancia\" \/><\/a><\/td>\r\n\t\t<\/tr>\r\n\t<\/tbody>\r\n<\/table>\r\n<\/body>\r\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-b0176f2 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"b0176f2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-24cdcc2 elementor-widget elementor-widget-text-editor\" data-id=\"24cdcc2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"0\" data-end=\"211\">By participating in the Proficiency Testing program, laboratories strengthen the traceability and reliability of their analyses, reduce health risks, and contribute directly to the protection of public health.<\/p><p data-start=\"213\" data-end=\"318\" data-is-last-node=\"\" data-is-only-node=\"\">To learn more about these and other programs that support analytical routines, access the <a href=\"https:\/\/controllab.com\/en\/catalog\/\" target=\"_blank\" rel=\"noopener\">online catalog<\/a>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Controllab\u2019s Proficiency Testing programs are strategic allies for evaluating laboratory routines and reinforcing the reliability of results. Pharmaceutical products require strict quality controls to ensure the<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":197277,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[551],"tags":[2682,2683,2673,658,669,2674,2685,2684,2681,2675,1828,2686],"class_list":["post-199161","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-microbiology","tag-control-de-calidad-en","tag-control-de-calidad-de-productos-farmaceuticos-en","tag-controle-da-qualidade-produtos-farmaceuticos-en","tag-controllab","tag-controllab-en","tag-medicamentos-en","tag-medicines","tag-pharmaceutical-products","tag-productos-farmaceuticos-en","tag-produtos-farmaceuticos-en","tag-controle-da-qualidade-en","tag-quality-control-of-pharmaceutical-products"],"acf":[],"_links":{"self":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/posts\/199161","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/comments?post=199161"}],"version-history":[{"count":6,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/posts\/199161\/revisions"}],"predecessor-version":[{"id":199272,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/posts\/199161\/revisions\/199272"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/media\/197277"}],"wp:attachment":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/media?parent=199161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/categories?post=199161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/tags?post=199161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}