{"id":202144,"date":"2025-10-28T11:58:59","date_gmt":"2025-10-28T14:58:59","guid":{"rendered":"https:\/\/controllab.com\/ensino\/resumos-cientificos\/avanco-dos-pocts-para-anti-hcv-14-anos-de-insights-de-qualidade-do-eqap-do-brasil-2010-2024\/"},"modified":"2025-10-30T10:42:49","modified_gmt":"2025-10-30T13:42:49","slug":"advancing-anti-hcv-point-of-care-testing-fourteen-years-of-quality-insights-from-brazils-eqap-2010-2024","status":"publish","type":"resumos","link":"https:\/\/controllab.com\/en\/learning\/scientific-abstracts\/advancing-anti-hcv-point-of-care-testing-fourteen-years-of-quality-insights-from-brazils-eqap-2010-2024\/","title":{"rendered":"Advancing Anti-HCV Point-of-Care Testing: Fourteen Years of Quality Insights from Brazil\u2019s EQAP (2010\u20132024)"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"202144\" class=\"elementor elementor-202144 elementor-201539\" data-elementor-post-type=\"resumos\">\n\t\t\t\t<div class=\"has_ae_slider elementor-element elementor-element-52fa95b e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"52fa95b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-497613b elementor-widget elementor-widget-heading\" data-id=\"497613b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Background - Aim<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-6c37069 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"6c37069\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7895077 elementor-widget elementor-widget-text-editor\" data-id=\"7895077\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p align=\"justify\">Hepatitis C virus (HCV) infection remains a global health challenge, causing chronic liver disease and approximately 400,000 deaths annually, with a high burden in low- and middle-income countries (LMICs). Anti-HCV detection is a standard screening tool, and point-of-care tests (POCT) offer rapid results to support timely decisions. External Quality Assessment Programs (EQAP) are vital for ensuring the reliability and comparability of test results.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-7763720 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"7763720\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-30cee02 elementor-widget elementor-widget-heading\" data-id=\"30cee02\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Methods<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-8eb7736 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"8eb7736\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-452a2b2 elementor-widget elementor-widget-text-editor\" data-id=\"452a2b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p align=\"justify\">Data from 2010 to 2024, spanning four annual rounds, were analyzed. Participants evaluated four lyophilized and\/or liquid quality control samples per round. Metrics included participation, adequacy rates (%A), inadequacy rates (%I), specificity (SP), and sensitivity (SE).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-0938366 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"0938366\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aefa88c elementor-widget elementor-widget-heading\" data-id=\"aefa88c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Results<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-20a43fa e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"20a43fa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1843587 elementor-widget elementor-widget-text-editor\" data-id=\"1843587\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A total of 290 participants contributed 16,828 datasets, with participation growing from 20 laboratories in 2010 to 121 in 2024 (p&lt;0.0000). Performance remained high over time, with overall %A 98.6%, %I 1.8%, SP 98.7%, and SE 99% (Figure 1).<\/p><p>Of 24 manufacturer kits, 18 achieved %A &gt; 98%, while 2 scored below 95%. Performance highlights for commonly used kits include:<\/p><ul><li>Manufacturer A: %A 98.3%, SP 97.9%, SE 98.9% (144 participants \u2013 4,522 datasets)<\/li><li>Manufacturer B: %A 99.7%, SP 99.9%, SE 99.4% (94 participants \u2013 3,133 datasets)<\/li><li>Manufacturer C: %A 99.5%, SP 99.7%, SE 99.2% (54 participants \u2013 1,512 datasets)<\/li><\/ul><p>Smaller datasets showed lower performance:<\/p><ul><li>Manufacturer D: %A 94.1%, SP 92.3%, SE 97.2% (8 participants \u2013 101 datasets)<\/li><li>Manufacturer E: %A 88.8%, SP 83.7%, SE 94.6% (6 participants \u2013 80 datasets) (Table 1)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-9e1e8ec e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"9e1e8ec\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f1cf99b elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"f1cf99b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1.png\" data-elementor-open-lightbox=\"yes\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MjAxNTU3LCJ1cmwiOiJodHRwczpcL1wvY29udHJvbGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcL0FydGlnby0zLUZpZ3VyYS0xLnBuZyJ9\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"544\" height=\"349\" src=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1.png\" class=\"attachment-large size-large wp-image-201557\" alt=\"Participa\u00e7\u00e3o e desempenho ao longo do tempo\" srcset=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1.png 544w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1-117x75.png 117w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1-480x308.png 480w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Figura-1-500x321.png 500w\" sizes=\"(max-width:767px) 480px, 544px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Figure1: Participation and performance overtime.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-fade5a8 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"fade5a8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4588d75 elementor-widget elementor-widget-image\" data-id=\"4588d75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1.png\" data-elementor-open-lightbox=\"yes\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MjAxNTYxLCJ1cmwiOiJodHRwczpcL1wvY29udHJvbGxhYi5jb21cL3dwLWNvbnRlbnRcL3VwbG9hZHNcL0FydGlnby0zLVRhYmVsYS0xLTEucG5nIn0%3D\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"793\" height=\"236\" src=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1.png\" class=\"attachment-large size-large wp-image-201561\" alt=\"Desempenho dos kits mais usados - Tabela 1\" srcset=\"https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1.png 793w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1-768x229.png 768w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1-150x45.png 150w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1-480x143.png 480w, https:\/\/controllab.com\/wp-content\/uploads\/Artigo-3-Tabela-1-1-500x149.png 500w\" sizes=\"(max-width:767px) 480px, (max-width:793px) 100vw, 793px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Table 1: Performance for more commonly used kits.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-6d1fc52 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"6d1fc52\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6934323 elementor-widget elementor-widget-heading\" data-id=\"6934323\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Conclusions<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-316e350 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"316e350\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1390674 elementor-widget elementor-widget-text-editor\" data-id=\"1390674\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p align=\"justify\">The growing adoption of POCT for anti-HCV in Brazil is evidenced by increased EQAP participation. High %A, SP, and SE, alongside low %I, confirm the reliability of POCT, matching traditional laboratory test standards. EQAP monitoring ensures robust performance and supports accurate HCV diagnostics.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-d81b10a e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"d81b10a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c2e06c4 elementor-widget elementor-widget-heading\" data-id=\"c2e06c4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">References<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"has_ae_slider elementor-element elementor-element-d9eb059 e-flex e-con-boxed ae-bg-gallery-type-default e-con e-parent\" data-id=\"d9eb059\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d78b436 elementor-widget elementor-widget-text-editor\" data-id=\"d78b436\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p align=\"justify\"><span style=\"font-family: Arial, serif;\"><span lang=\"en-US\">Updated recommendations on simplified service delivery and disagnostics for hepatitis C infection: policy brief. ISBN978-92-4-005269-7(electronicversion). ISBN978-92-4-005270-3 (printversion) \u00a9WorldHealthOrganization 2022.<\/span><\/span><\/p><p align=\"justify\"><span style=\"font-family: Arial, serif;\"><span lang=\"en-US\">C.Vassalle, A.Mercuri, S.Masini, S.Antongiovanni, A.Pilo, F.Cantini, G.C.Zucchelli. External quality assurance program in anti-HCV serological detection: an Italian experience. <\/span><\/span><span style=\"font-family: Arial, serif;\"><span lang=\"fr-FR\">Immuno-analyse &amp; Biologie Sp\u00e9cialis\u00e9e, Volume19, Issue4, 2004, Pages 235-238, ISSN 0923-2532, https:\/\/doi.org\/10.1016\/j.immbio.2004.05.001.<\/span><\/span><\/p><p align=\"justify\"><span style=\"font-family: Arial, serif;\"><span lang=\"fr-FR\">Carvalho-Gomes \u00c2, Cubells A, Pallar\u00e9s C, Hontangas V, CondeI, Di Maira T, Peir\u00f3 S, Sanf\u00e9lix-Gimeno G, L\u00f3pez-Labrador FX, Berenguer M. Apopulation-based screening for hepatitis C antibodies and active infection using a point-of-care testin a low prevalence area. <\/span><\/span><span style=\"font-family: Arial, serif;\"><span lang=\"en-US\">PLoS One. 2020 Feb11;15(2): e0228351. doi:10.1371\/journal.pone.0228351. PMID:32045417; PMCID: PMC7012430.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>A. Ferreira4, L. Bottino1, M. Souza1, L. Pereira1, E. Santiago1, A. Vieira1, L. Vasconcellos2, \u00c1. Pulchinelli3, R. Sykora4, M. Moreira1, J. Poloni1, V. Biasoli1<\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false},"tags":[2770,2771,1396],"class_list":["post-202144","resumos","type-resumos","status-publish","hentry","tag-anti-hcv","tag-eqap","tag-poct-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/resumos\/202144","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/resumos"}],"about":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/types\/resumos"}],"wp:attachment":[{"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/media?parent=202144"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/controllab.com\/en\/wp-json\/wp\/v2\/tags?post=202144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}