Dengue diagnosis: why is the reliability of reports essential?

Dengue diagnosis: why is the reliability of reports essential?

Dengue diagnosis: why is the reliability of reports essential?

A importância da precisão dos laudos no controle da Dengue

The analytical quality of tests directly impacts the accuracy of diagnosis and the safety of clinical decisions.

According to the Pan American Health Organization (PAHO), to date, the number of dengue cases in Latin America and Brazil has not exceeded the figures recorded during the same period in 2024. However, considering last year’s record increase, countries in the region begin 2025 on alert for the possibility of a new outbreak.

Factors such as climate change, uncontrolled urbanization, and improper waste management continue to drive the proliferation of the Aedes aegypti mosquito, the disease vector. In this context, services performing the test must prepare for a potential increase in demand for these analyses.

Correct identification of dengue cases and differentiation of serotypes are crucial for effective diagnosis, considering the disease’s varied manifestations, ranging from asymptomatic to severe, with a risk of death. Therefore, analytical quality in tests is essential to avoid errors that could compromise medical decisions.

Comprehensive solutions for accurate reports

In light of the potential high demand for dengue tests, services must ensure the reliability of analytical processes to issue secure reports. Controllab, a leader in laboratory quality control in Latin America, offers comprehensive solutions for various dengue detection methodologies, such as serologies (IgG, IgM, NS1 Antigen), molecular biology, and POCT (Point-of-Care Testing).

Highlights of the Proficiency Test for Dengue

For the Proficiency Testing (EP), also known as External Quality Control (EQC), in the Dengue – Molecular Biology program, participants identify the serotype through genotyping. The PT Sequencing: Viral Genome Detection sends alternating samples of epidemiologically relevant viruses, including the dengue serotypes.

Reliability in dengue testing with external and internal quality control

In addition to External Control, the reliability of diagnostic routines depends on continuous monitoring with Internal Control (CI) of quality.

Controllab provides third-party internal controls that make a difference. These materials identify variations that may be overlooked by manufacturers of analytical systems, offering more reliable analysis. These controls typically include interlaboratory results from different systems and faithfully reproduce the performance of patient samples.

Discover Controllab’s programs that ensure more reliable reports and more effective control of the dengue analytical routine:

Programs

Available tests

Available services

Dengue
  • Serology of IgG and IgM antibodies (automation)

Proficiency TestingInternal Control
Dengue NS1
  • NS1 Antigen (automation)

Proficiency TestingInternal Control
Dengue – Molecular Biology
  • Detection and Genotyping of Types 1, 2, 3, and 4

Ensaio de ProficiênciaInternal Control
Sequencing: Viral Genome Detection
  • Genotypic identification of epidemiologically relevant viruses

Proficiency Testing
POCT Dengue
  • Serology of IgG and IgM antibodies

Proficiency Testing
POCT Dengue NS1
  • NS1 Antigen

Proficiency Testing Internal Control
Incorporate certified batches into your dengue POCT analytical routine

The Lot-by-Lot Certification Program has strengthened confidence in the analytical routines of POCT devices. It validates the performance of new batches compared to previous ones, reducing costs and efforts to monitor reagent changes, while ensuring the quality and reliability of the tests.

Certification prevents the inclusion of batches with deviations that could compromise results. This provides greater confidence in your routine and enhanced safety for your patients. To identify certified batches for dengue, please access this link.

Dengue and Other Arboviral Diseases

In addition to dengue, it is essential to maintain a reliable analytical routine to detect other circulating arboviral diseases, such as Chikungunya, Zika, and Oropouche. These tests are crucial for differential diagnosis and serve as exclusion criteria in clinical investigations, assisting doctors and laboratories in making more accurate and secure decisions.
To support the precise detection of these diseases, Controllab offers solutions that enhance the reliability of analytical processes:

POCT Zika Virus – Immunology
Zika Virus – Molecular Biology
Zika Virus – Immunology
Chikungunya – Molecular Biology
Chikungunya – Immunology
Oropouche Virus – Molecular Biology

Portrait of smiling doctor using digital tablet in hospital corridor

Looking for more reliability in your dengue tests?

Contact a Controllab specialist now and discover how to enhance the quality of your analyses.

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PRM 0009

Certified Reference Material Producer

Accredited by Coordenação-Geral de Acreditação do Inmetro

Controllab has been accredited as a Certified Reference Material (CRM) Producer since 2016 by Cgcre, under number PMR 0009. The conformity assessment is carried out in accordance with the requirements established in ABNT NBR ISO 17034 and Inmetro standards, ensuring competence for the production of CRMs, as defined in the Scope of Accreditation.

This accreditation attests to Controllab’s technical competence in producing CRMs according to international requirements and enables it to be recognized in other countries, under mutual recognition agreements, thereby reducing technical barriers between Brazil and other countries across continents.

Materiais de Referência Certificados - PMR 0009 - ABNT NBR ISO 17034-Controllab
Cgcre is signatory to the Mutual Recognition Arrangements of the International Laboratory Accreditation Cooperation (ILAC) and Interamerican Accreditation Cooperation (IAAC).

CAL 0214

Calibration Laboratory

Accredited by Coordenação-Geral de Acreditação do Inmetro

In December 2002, the Calibration Laboratory was accredited by Cgcre. With this recognition, it became part of the Brazilian network of accredited laboratories, under number 214. Since then, it has been periodically evaluated for the maintenance and/or extension of its accreditation.

The Inmetro seal attests to Controllab’s technical competence, credibility, and operational capability for calibration services, in accordance with the requirements of ABNT NBR ISO/IEC 17025.

Calibração de Instrumentos - CAL 0214 - ABNT NBR ISO/IEC 17025 - Controllab
Cgcre is signatory to the Mutual Recognition Arrangements of the International Laboratory Accreditation Cooperation (ILAC) and Interamerican Accreditation Cooperation (IAAC).

PEP 0003

Proficiency Test Provider

Accredited by Coordenação-Geral de Acreditação do Inmetro

In September 2011, Controllab was accredited by Cgcre as a proficiency test provider, under nº PEP0003. Initially as part of a pilot project by Inmetro, this accreditation was based on ILAC G13: 2007 and included several clinical and hemotherapy tests. In the periodic evaluations of this accreditation, new segments and tests are included and the evaluation is now conducted according to ABNT NBR ISO/IEC 17043.

This accreditation attests to Controllab’s technical competence to develop and conduct proficiency tests in accordance with international requirements and enables it to be recognized in other countries, in accordance with mutual recognition agreements signed by Brazil in Mercosur, the Americas and Europe.

PEP 0003 - ABNT NBR ISO-IEC 17043 - Controllab

Cgcre is signatory to the Mutual Recognition Arrangements of the International Laboratory Accreditation Cooperation (ILAC) and Interamerican Accreditation Cooperation (IAAC).